منابع مشابه
Thyroglobulin Processing by Thyroidal Proteases
The normal provision of thyroid hormones to the body requires their release from the prohormone, thyroglobulin (Tg). Previous work established the importance of cathepsins B, D, and L (formerly designated cysteine proteinase I) to this process but had not defined the points of proteolytic attack for each enzyme. In the present study we labeled rabbit Tg in vivo with sodium ‘‘‘1 and performed li...
متن کاملConstipation
Bigg, p.r.c.s.e. London : Balliere, Tindall it Cox, 1902. Pp. 67. Cr. 8vo. Price, 2s. 6d. This is an admirable little book describing in simple language constipation, its causation, widespread prevalence and its treatment. Constipation is a complaint which is not confined to one class nor any one age, it affects all classes of men, women and children. Our author is very sound in his advice, and...
متن کاملRadioiodine-treatment (RIT) of functional thyroidal autonomy.
Since 1942, therapy with radioiodine (RIT) has gained a major role in the treatment of benign thyroid disorders, notably hyperthyroidism caused by Graves' disease or toxic multinodular goitre (thyroid autonomy). In iodine deficient areas thyroid autonomy accounts for 40-50% of all cases with hyperthyroidism. RIT has become a cost-effective first-line procedure in autonomy-patients with latent o...
متن کاملIncreased Thyroxine Turnover and Thyroidal Function
A B S T R A C T Administration of phenobarbital to rats in a dosage schedule previously demonstrated to increase hepatocellular binding of thyroxine results in increased hormonal turnover, due both to increased deiodination and to fecal disposition of thyroxine iodine. The rate of biliary excretion of thyroxine iodine is roughly proportional to the hepatic content of exchangeable thyroxine. The...
متن کاملNon-Thyroidal Illness: Physiopathology and Clinical Implications
In critical illness, several abnormalities in thyroid hormone (TH) secretion, metabolism and action have been described in patients without previous diagnosis of intrinsic thyroid disease and are collectively called “Non thyroidal syndrome” (NTIS) [1]; this term is now largely employed, in the place of “euthyroid sick syndrome” [2-4] or “low-T3 syndrome”, due to the most common abnormality, a d...
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ژورنال
عنوان ژورنال: The Journal of Nervous and Mental Disease
سال: 1920
ISSN: 0022-3018
DOI: 10.1097/00005053-192008000-00009